Latent Class Analysis to Predict Outcomes of Early High-Intensity Physical Therapy After Total Knee Arthroplasty, Based on Longitudinal Trajectories of Walking Speed
Publication year
2021Source
Journal of Orthopaedic and Sports Physical Therapy, 51, 7, (2021), pp. 362-371ISSN
Publication type
Article / Letter to editor
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Organization
Health Evidence
IQ Healthcare
Orthopaedics
Rehabilitation
Journal title
Journal of Orthopaedic and Sports Physical Therapy
Volume
vol. 51
Issue
iss. 7
Page start
p. 362
Page end
p. 371
Subject
Radboudumc 17: Women's cancers RIHS: Radboud Institute for Health Sciences; Radboudumc 18: Healthcare improvement science RIHS: Radboud Institute for Health Sciences; IQ Healthcare - Radboud University Medical Center; Orthopaedics - Radboud University Medical Center; Rehabilitation - Radboud University Medical CenterAbstract
OBJECTIVE: To (1) classify patients who are recovering from total knee arthroplasty (TKA) based on walking speed during an early physical therapy program, and (2) assess whether walking-speed trajectory predicts performance on the timed up-and-go (TUG) test. DESIGN: Cohort study. METHODS: We included 218 patients from a 10-day physical therapy program after TKA. A latent class mixed model was used to classify patients according to their walking-speed trajectory during the program. We assessed the change in TUG test score from pre-TKA to 6 weeks and 1 year after TKA. The association between change in TUG test score and walking-speed trajectory was assessed using multivariable regression. RESULTS: There were 2 groups with distinct walking-speed trajectories: a high-gain group (46%) and a low-gain group (54%). There was no significant association between change in TUG test score and walking-speed trajectory after TKA and physical therapy. Function (based on TUG test performance) improved for all patients 1 year after TKA, irrespective of walking-speed trajectory (ie, high or low gain) early in postoperative physical therapy. CONCLUSION: Although we distinguished different groups based on functional outcomes during physical therapy, the clinical relevance of classifying patients based on walking speed remains unclear, as it did not predict short- and long-term functional outcomes. J Orthop Sports Phys Ther 2021;51(7):362-371. Epub 10 May 2021. doi:10.2519/jospt.2021.10299.
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