Validity of the Mini-Mental State Examination-2 in diagnosing mild cognitive impairment and dementia in patients visiting an outpatient clinic in the Netherlands
Publication year
2020Author(s)
Number of pages
4 p.
Source
Alzheimer Disease & Associated Disorders, 34, 3, (2020), pp. 278-281ISSN
Publication type
Article / Letter to editor

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Organization
SW OZ DCC NRP
Medical Psychology
Journal title
Alzheimer Disease & Associated Disorders
Volume
vol. 34
Issue
iss. 3
Languages used
English (eng)
Page start
p. 278
Page end
p. 281
Subject
All institutes and research themes of the Radboud University Medical Center; Neuropsychology and rehabilitation psychology; Radboudumc 1: Alzheimer`s disease DCMN: Donders Center for Medical Neuroscience; Neuro- en revalidatiepsychologieAbstract
This study examined the utility of the recently published MMSE-2:SV in detecting cognitive impairment. We used receiver operating characteristics to test the discriminative power of the MMSE-2:SV for distinguishing between older adults without mild cognitive impairment (MCI) or dementia (n=67) and patients with MCI (n=76) or dementia (n=79). The results show that the MMSE-2:SV had excellent discriminative ability in distinguishing older controls from patients with dementia, with cut-off scores of 26 and 27 (max=30) yielding appropriate sensitivity (0.810 and 0.924, respectively) and specificity (0.940 and 0.806). Discriminative power was close to good in distinguishing between older controls and patients with MCI. Here, however, no optimal cut-off point could be determined. Even though this study shows good sensitivity and adequate specificity for the MMSE-2:SV in discriminating individuals without MCI or dementia from those with dementia, its validity is limited for identifying patients with MCI.
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- Academic publications [203793]
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- Faculty of Medical Sciences [80320]
- Faculty of Social Sciences [27292]
- Open Access publications [70806]
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