Differences in hair cortisol concentrations and reported anxiety in women with preeclampsia versus uncomplicated pregnancies
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Number of pages
SourcePregnancy Hypertension, 21, (2020), pp. 200-202
Article / Letter to editor
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SW OZ BSI ON
PI Group Memory and Emotion
SubjectAll institutes and research themes of the Radboud University Medical Center; Radboudumc 0: Other Research RIHS: Radboud Institute for Health Sciences; Radboudumc 10: Reconstructive and regenerative medicine RIMLS: Radboud Institute for Molecular Life Sciences; Radboudumc 13: Stress-related disorders DCMN: Donders Center for Medical Neuroscience; Social Development
This Dutch multicenter case-controlled study investigated whether cortisol concentrations and psychosocial stress during pregnancy differed between women with early-onset preeclampsia, late-onset preeclampsia, and uncomplicated pregnancies. Cortisol concentrations were analyzed in three hair segments representing the preconception period, first, and second trimester of pregnancy. Cortisol trajectories differed, with early-onset preeclampsia showing steeper increases in cortisol and higher cortisol concentrations during the second trimester. Reported anxiety in women with preeclampsia was higher compared to women with uncomplicated pregnancies. These results indicate that measures of cortisol and reported anxiety differ between early-onset, late-onset preeclampsia, and uncomplicated pregnancies.
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