Neural correlates of retrieval-based enhancement of autobiographical memory in older adults
Publication year
2020Source
Scientific Reports, 10, (2020), article 1447ISSN
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Publication type
Article / Letter to editor
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Organization
Medical Imaging
Cognitive Neuroscience
Journal title
Scientific Reports
Volume
vol. 10
Subject
Radboudumc 13: Stress-related disorders DCMN: Donders Center for Medical NeuroscienceAbstract
Lifelog photo review is considered to enhance the recall of personal events. While a sizable body of research has explored the neural basis of autobiographical memory (AM), there is limited neural evidence on the retrieval-based enhancement effect on event memory among older adults in the real-world environment. This study examined the neural processes of AM as was modulated by retrieval practice through lifelog photo review in older adults. In the experiment, blood-oxygen-level dependent response during subjects' recall of recent events was recorded, where events were cued by photos that may or may not have been exposed to a priori retrieval practice (training). Subjects remembered more episodic details under the trained relative to non-trained condition. Importantly, the neural correlates of AM was exhibited by (1) dissociable cortical areas related to recollection and familiarity, and (2) a positive correlation between the amount of recollected episodic details and cortical activation within several lateral temporal and parietal regions. Further analysis of the brain activation pattern at a few regions of interest within the core remember network showed a training_condition x event_detail interaction effect, suggesting that the boosting effect of retrieval practice depended on the level of recollected event details.
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- Academic publications [238586]
- Electronic publications [122804]
- Faculty of Medical Sciences [90409]
- Open Access publications [97790]
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