Subject:
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220 Statistical Imaging Neuroscience Action, intention, and motor control Neuroinformatics Radboudumc 7: Neurodevelopmental disorders DCMN: Donders Center for Medical Neuroscience |
Organization:
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SW OZ DCC SMN Cognitive Neuroscience PI Group Memory and Emotion PI Group Statistical Imaging Neuroscience Neuroinformatics |
Abstract:
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To compare findings across species, neuroscience relies on cross-species homologies, particularly in terms of brain areas. For cingulate cortex, a structure implicated in behavioural adaptation and control, a homologous definition across mammals is available - but currently not employed by most rodent researchers. The standard partitioning of rodent cingulate cortex is inconsistent with that in any other model species, including humans. Reviewing the existing literature, we show that the homologous definition better aligns results of rodent studies with those of other species, and reveals a clearer structural and functional organisation within rodent cingulate cortex itself. Based on these insights, we call for widespread adoption of the homologous nomenclature, and reinterpretation of previous studies originally based on the nonhomologous partitioning of rodent cingulate cortex.
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