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      Physiological parameters for three farm animal species (cattle, sheep, and swine) as the basis for the development of generic physiologically based kinetic models

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      Creators
      Lautz, L.S.
      Date of Archiving
      2019
      Archive
      Zenodo
      DOI
      https://doi.org/10.5281/zenodo.3693572
      Related publications
      Generic physiologically based kinetic modelling for farm animals: Part II. Predicting tissue concentrations of chemicals in swine, cattle, and sheep  
      Publication type
      Dataset
      Access level
      Open access
      Please use this identifier to cite or link to this item: https://hdl.handle.net/2066/217918   https://hdl.handle.net/2066/217918
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      Organization
      Environmental Science
      Audience(s)
      Agriculture and the physical environment
      Biology
      Key words
      farm animals; physiology; blood flow; organ; meta-analysis
      Abstract
      This excel file (DOI: 10.5281/zenodo.3433224) provides physiological parameters and their inter-individual variability (mean, coefficient of variation, sample size) for three farm animal species: cattle (Bos taurus), sheep (Ovis aries), and swine (Sus scrofa domesticus). These physiological parameters were estimated based on the results of extensive literature searches and specific experimental data described in Lautz et al., (2020). This file is associated with R codes (DOI: 10.5281/zenodo.3432796) for generic PBK models, partition coefficient Quantitative Structure Activity Relationship (QSAR) models for each farm animal species and parameterisation of the model. The full data collection and implementation of the models using case studies are described in Lautz et al., 2020 (10.1016/j.toxlet.2019.10.008).
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