Mandibular reconstruction: a clinical and radiographic animal study on the use of autogenous scaffolds and platelet-rich plasma.
SourceInternational Journal of Oral and Maxillofacial Surgery, 31, 3, (2002), pp. 281-286
Article / Letter to editor
Display more detailsDisplay less details
Oral and Maxillofacial Surgery
Periodontology and Biomaterials
International Journal of Oral and Maxillofacial Surgery
SubjectSurgical Oncology; Growth and development of the orofacial region; Implantology and biomaterials; Chirurgische Oncologie; Groei en ontwikkeling van het orofaciale gebied; Implantologie en biomaterialen
This paper reports on an experimental animal study evaluating a method of mandibular reconstruction. After a successful pilot study, 28 goats underwent a continuity resection of the mandibular angle. Primary reconstruction was carried out using specially designed osteosynthesis plates and screws. The defect was bridged by the original cortical scaffold, filled with an autogenous bone graft from the iliac crest. To accelerate bone healing, platelet-rich plasma (PRP) was mixed with the particulate bone graft in 14 goats. All goats had uneventful healing. The osteosynthesis plates and screws withstood immediate loading for periods varying from 3 weeks to 3 months. The use of PRP appeared to enhance bone healing considerably.
Upload full text