Fatal hemorrhagic pneumonia caused by infection due to Kytococcus sedentarius-a pathogen or passenger?
SourceAnnals of Hematology, (2003)
Article / Letter to editor
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Blood Transfusion and Transplantation Immunology
Annals of Hematology
SubjectUMCN 1.3: Tumor microenvironment; UMCN 1.4: Immunotherapy, gene therapy and transplantation; UMCN 1.5: Interventional oncology; UMCN 4.1: Microbial pathogenesis and host defense
A 55-year old man developed a hemorrhagic pneumonia, likely due to infection with Kytococcus sedentarius during neutropenia following induction chemotherapy for acute myeloid leukemia. Severe mucosal barrier injury and the selective pressure of broad-spectrum antibiotics probably made it possible for this normally harmless commensal to penetrate the gut, spread through the blood stream, and invade the lungs.
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