The value of FDG-PET CT scans to evaluate bone marrow in haemato-oncological conditions

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Title:	The value of FDG-PET CT scans to evaluate bone marrow in haemato-oncological conditions
Author(s):	Son, P.M. van; Evers, D. ; Aarntzen, E.H.J.G.
Publication year:	2019
Source:	Netherlands Journal of Medicine, vol. 77, iss. 7, (2019), pp. 234-242
ISSN:	0300-2977
Publication type:	Article / Letter to editor
Please use this identifier to cite or link to this item : https://hdl.handle.net/2066/214891
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Subject:	Radboudumc 16: Vascular damage RIHS: Radboud Institute for Health Sciences Radboudumc 4: lnfectious Diseases and Global Health RIMLS: Radboud Institute for Molecular Life Sciences
Organization:	Haematology Radiology & Nuclear Medicine
Journal title:	Netherlands Journal of Medicine
Volume:	vol. 77
Issue:	iss. 7
Page start:	p. 234
Page end:	p. 242
Abstract:	In the past decade, 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography (18F-FDG PET-CT) scans have been increasingly implemented in the diagnostic process of several haemato-oncological conditions. Accurate assessment of bone marrow activity observed on 18F-FDG PET-CT is crucial for a correct diagnostic conclusion, subsequent treatment decision, and follow-up strategies. By systematically considering the arguments of the level of 18F-FDG uptake, distribution pattern, coinciding changes of the bone structure, and the clinical context, interpretation and validity may improve. This review aims to give a comprehensive overview of the different patterns of 18F-FDG uptake on PET/CT in common benign, clonal, and malignant haematological conditions, accompanied by illustrative cases.