Imaging strategies in the management of gastric cancer: current role and future potential of MRI
Publication year
2019Source
British Journal of Radiology, 92, 1097, (2019), pp. 20181044ISSN
Publication type
Article / Letter to editor

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Organization
Radiation Oncology
Journal title
British Journal of Radiology
Volume
vol. 92
Issue
iss. 1097
Page start
p. 20181044
Subject
Radboudumc 9: Rare cancers RIHS: Radboud Institute for Health SciencesAbstract
Accurate preoperative staging of gastric cancer and the assessment of tumor response to neoadjuvant treatment is of importance for treatment and prognosis. Current imaging techniques, mainly endoscopic ultrasonography (EUS), computed tomography (CT) and (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET), have their limitations. Historically, the role of magnetic resonance imaging (MRI) in gastric cancer has been limited, but with the continuous technical improvements, MRI has become a more potent imaging technique for gastrointestinal malignancies. The accuracy of MRI for T- and N-staging of gastric cancer is similar to EUS and CT, making MRI a suitable alternative to other imaging strategies. There is limited evidence on the performance of MRI for M-staging of gastric cancer specifically, but MRI is widely used for diagnosing liver metastases and shows potential for diagnosing peritoneal seeding. Recent pilot studies showed that treatment response assessment as well as detection of lymph node metastases and systemic disease might benefit from functional MRI (e.g. diffusion weighted imaging and dynamic contrast enhancement). Regarding treatment guidance, additional value of MRI might be expected from its role in better defining clinical target volumes and setup verification with MR-guided radiation treatment.
This item appears in the following Collection(s)
- Academic publications [227437]
- Electronic publications [107154]
- Faculty of Medical Sciences [86157]
- Open Access publications [76295]
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