Oxytocin receptor gene (OXTR) and deviant peer affiliation: A gene-environment interaction in adolescent antisocial behavior
Publication year
2019Author(s)
Number of pages
16 p.
Source
Journal of Youth and Adolescence, 48, 1, (2019), pp. 86-101ISSN
Publication type
Article / Letter to editor
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Organization
SW OZ BSI OGG
Journal title
Journal of Youth and Adolescence
Volume
vol. 48
Issue
iss. 1
Languages used
English (eng)
Page start
p. 86
Page end
p. 101
Subject
Developmental PsychopathologyAbstract
Although the oxytocin receptor gene (OXTR) is involved in aggression and social affiliation, it has not been examined in gene-environment interaction studies. This longitudinal study examined the effect of genetic variants in OXTR and its gene-environment interaction with perceived deviant peer affiliation in the trajectories of antisocial behavior in 323 adolescents (182 males) from 13 to 18 years. Annual assessments of reactive and proactive aggression, delinquency, and friends’ delinquency, as well as DNA at age 17 were collected. Gene-based tests yielded no main effect of OXTR, but revealed a significant gene-environment interaction in proactive aggression and delinquency. Variation in the OXTR might affect the influence of deviant peer affiliation on antisocial behavior, contributing to a better understanding of individual differences in antisocial behavior.
This item appears in the following Collection(s)
- Academic publications [245054]
- Electronic publications [132354]
- Faculty of Social Sciences [30330]
- Open Access publications [105958]
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