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Publication year
2018Source
Cell, 175, 6, (2018), pp. 1463-1465ISSN
Publication type
Article / Letter to editor

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Organization
Internal Medicine
Journal title
Cell
Volume
vol. 175
Issue
iss. 6
Page start
p. 1463
Page end
p. 1465
Subject
Radboudumc 4: lnfectious Diseases and Global Health RIMLS: Radboud Institute for Molecular Life SciencesAbstract
Trained innate immunity mediates protection against heterologous infections and is mediated by epigenetic and functional reprogramming of myeloid cells and their progenitors. Now, Yao et al. describe trained immunity induced locally in alveolar macrophages by a viral infection, with IFNgamma release from effector CD8(+) lymphocytes initiating this process.
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- Faculty of Medical Sciences [86219]
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