Subject:
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Action, intention, and motor control All institutes and research themes of the Radboud University Medical Center DI-BCB_DCC_Theme 2: Perception, Action and Control DI-BCB_DCC_Theme 3: Plasticity and Memory Neuropsychology and rehabilitation psychology Radboudumc 13: Stress-related disorders DCMN: Donders Center for Medical Neuroscience Radboudumc 17: Women's cancers RIHS: Radboud Institute for Health Sciences Neuro- en revalidatiepsychologie Tijdelijke code tbv inlezen publicaties Radboudumc - Alleen voor gebruik door Radboudumc |
Organization:
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Anatomy SW OZ DCC NRP SW OZ DCC SMN Gynaecology |
Abstract:
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Objective: To investigate alterations in tactile, pain thresholds and pain tolerance thresholds in patients with endometriosis using a multimodality approach. Design: Cross-sectional study. Setting: Multidisciplinary referral center. Patient(s): Women with proven endometriosis (N = 35) and healthy controls (N = 38). Intervention(s): Pain processing was tested using quantitative sensory testing (QST) to investigate sensation, pain, and pain tolerance thresholds for thermal, electrical, and pressure stimuli. Main Outcome Measure(s): Differences in QST measures in patients with endometriosis and in healthy controls on the endometriosis site and control sites, and the association between QST outcomes and patient characteristics. Result(s): We observed a significantly decreased pain tolerance in patients with endometriosis, independent of clinical pain intensity or revised American Society for Reproductive Medicine stage, compared with healthy controls. Conclusion(s): Increasing knowledge concerning mechanisms underlying the pain of women with endometriosis creates opportunities to develop new treatment options. More attention should be paid not only to treat endometriosis in a surgical or pharmacologic way, but also to desensitize by pain education or cognitive therapy.
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