Stimulus familiarity and expectation jointly modulate neural activity in the visual ventral stream
Number of pages
SourceJournal of Cognitive Neuroscience, 30, 9, (2018), pp. 1366-1377
Article / Letter to editor
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PI Group Predictive Brain
SW OZ DCC CO
PI Group Neurobiology of Language
Journal of Cognitive Neuroscience
Subject110 000 Neurocognition of Language; 180 000 Predictive Brain; Action, intention, and motor control; DI-BCB_DCC_Theme 2: Perception, Action and Control
Prior knowledge about the visual world can change how a visual stimulus is processed. Two forms of prior knowledge are often distinguished: stimulus familiarity (i.e., whether a stimulus has been seen before) and stimulus expectation (i.e., whether a stimulus is expected to occur, based on the context). Neurophysiological studies in monkeys have shown suppression of spiking activity both for expected and for familiar items in object-selective inferotemporal cortex. It is an open question, however, if and how these types of knowledge interact in their modulatory effects on the sensory response. To address this issue and to examine whether previous findings generalize to noninvasively measured neural activity in humans, we separately manipulated stimulus familiarity and expectation, whereas noninvasively recording human brain activity using magnetoencephalography. We observed independent suppression of neural activity by familiarity and expectation, specifically in the lateral occipital complex, the putative human homologue of monkey inferotemporal cortex. Familiarity also led to sharpened response dynamics, which was predominantly observed in early visual cortex. Together, these results show that distinct types of sensory knowledge jointly determine the amount of neural resources dedicated to object processing in the visual ventral stream.
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