ADHD symptoms in healthy adults are associated with stressful life events and negative memory bias
Publication year
2018Author(s)
Number of pages
10 p.
Source
Attention Deficit and Hyperactivity Disorders, 10, 2, (2018), pp. 151-160ISSN
Publication type
Article / Letter to editor
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Organization
Psychiatry
SW OZ BSI KLP
Medical Imaging
PI Group Memory & Emotion
Cognitive Neuroscience
Human Genetics
Journal title
Attention Deficit and Hyperactivity Disorders
Volume
vol. 10
Issue
iss. 2
Languages used
English (eng)
Page start
p. 151
Page end
p. 160
Subject
130 000 Cognitive Neurology & Memory; Experimental Psychopathology and Treatment; Radboudumc 13: Stress-related disorders DCMN: Donders Center for Medical Neuroscience; Radboudumc 14: Tumours of the digestive tract RIMLS: Radboud Institute for Molecular Life Sciences; Radboudumc 7: Neurodevelopmental disorders DCMN: Donders Center for Medical Neuroscience; Cognitive Neuroscience - Radboud University Medical Center; Human Genetics - Radboud University Medical Center; Psychiatry - Radboud University Medical Center; Radboud University Medical CenterAbstract
Stressful life events, especially Childhood Trauma, predict ADHD symptoms. Childhood Trauma and negatively biased memory are risk factors for affective disorders. The association of life events and bias with ADHD symptoms may inform about the etiology of ADHD. Memory bias was tested using a computer task in N = 675 healthy adults. Life events and ADHD symptoms were assessed using questionnaires. The mediation of the association between life events and ADHD symptoms by memory bias was examined. We explored the roles of different types of life events and of ADHD symptom clusters. Life events and memory bias were associated with overall ADHD symptoms as well as inattention and hyperactivity/impulsivity symptom clusters. Memory bias mediated the association of Lifetime Life Events, specifically Childhood Trauma, with ADHD symptoms. Negatively biased memory may be a cognitive marker of the effects of Childhood Trauma on the development and/or persistence of ADHD symptoms.
This item appears in the following Collection(s)
- Academic publications [243908]
- Donders Centre for Cognitive Neuroimaging [3982]
- Electronic publications [130658]
- Faculty of Medical Sciences [92803]
- Faculty of Social Sciences [30014]
- Open Access publications [104946]
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