Plasmodium falciparum: Membrane feeding assays and competition ELISAs for the measurement of transmission reduction in sera from Cameroon.
SourceExperimental Parasitology, 92, (1999), pp. 81-86
Article / Letter to editor
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SubjectMalaria: parasite-host interaction; Malaria: gastheer-parasiet interactie
Epidemiological studies on the infectivity of Plasmodium falciparum gametocyte carriers to mosquitoes are important to estimate the human reservoir in malaria endemic areas and to evaluate the impact of conatrol measures aiming at reduction of malaria transmission. Muirhead Thomson (1957) investigated infectivity through direct feeding of batches of Anopheles gambiae on human subjects. Recent field studies used a similar approach (Gamage-Mendis et al. 1991; Githeka et al. 1992), but for ethical and practical reasons preference is often given to membrane feeding with blood from gametocyte carriers.
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