Pd-catalysed synthesis of 5-substituted proline derivatives from acetylene-containing amino acids
Number of pages
SourceSynlett, 2003, 15, (2003), pp. 2354-2358
Article / Letter to editor
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Synthetic Organic Chemistry
Solid State Chemistry
SubjectSynthetic Organic Chemistry
2,5-Disubstituted pyrrolines have been synthesised via Pd-catalysed 5-endo-dig cyclisations of substituted acetylene-containing amino acids. It has also been shown that these pyrrolines can be efficiently transformed into the corresponding saturated proline derivatives.
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