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Title: MMP9 potentiates pulmonary metastasis formation.
Author(s): Kempen, L.C.L.T. van ; Coussens, L.M.
Publication year: 2002
Source: Cancer Cell, vol. 2, iss. 4, (2002), pp. 251-252
ISSN: 1535-6108
DOI: https://doi.org/10.1016/S1535-6108(02)00157-5
Publication type: Article / Letter to editor

Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/186614   http://hdl.handle.net/2066/186614

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Subject: Tumor pathology
Tumor pathologie
Organization: Pathology
Journal title:
Cancer Cell
Volume: vol. 2
Issue: iss. 4
Page start: p. 251
Page end: p. 252
Abstract:
Tumor cell dissemination to distant organ sites is a complex process involving multiple cell types, soluble growth factors, adhesion receptors, and tissue remodeling. A new study in this issue of Cancer Cell shows that MMP9-expressing tumor-associated macrophages play a key role in prepping premetastatic sites for eventual malignant cell growth in a manner dependent upon vascular endothelial growth factor receptor-1 (VEGFR-1).

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