Publication year
2002Source
Cancer Cell, 2, 4, (2002), pp. 251-2ISSN
Publication type
Article / Letter to editor

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Organization
Pathology
Journal title
Cancer Cell
Volume
vol. 2
Issue
iss. 4
Page start
p. 251
Page end
p. 2
Subject
Tumor pathology; Tumor pathologieAbstract
Tumor cell dissemination to distant organ sites is a complex process involving multiple cell types, soluble growth factors, adhesion receptors, and tissue remodeling. A new study in this issue of Cancer Cell shows that MMP9-expressing tumor-associated macrophages play a key role in prepping premetastatic sites for eventual malignant cell growth in a manner dependent upon vascular endothelial growth factor receptor-1 (VEGFR-1).
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