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Publication year
1999Source
Trends in Microbiology, 7, 7, (1999), pp. 281-91ISSN
Publication type
Article / Letter to editor
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Organization
Bioinformatics
Journal title
Trends in Microbiology
Volume
vol. 7
Issue
iss. 7
Page start
p. 281
Page end
p. 91
Subject
Study of abnormal differentiation and transformation processes in heritable and acquired disorders with the use of cell and animal models; Bestudering van abnormale differentiatie en transformatieprocessen bij erfelijke of verworven aandoeningen m.b.v. cel- en diermodellenAbstract
The presence of genes encoding enzymes involved in the citric-acid cycle has been studied in 19 completely sequenced genomes. In the majority of species, the cycle appears to be incomplete or absent. Several distinct, incomplete cycles reflect adaptations to different environments. Their distribution over the phylogenetic tree hints at precursors in the evolution of the citric-acid cycle.
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