Clinical thermometry, using the 27 MHz multi-electrode current-source interstitial hyperthermia system in brain tumours.
SourceRadiotherapy and Oncology, 59, 2, (2001), pp. 227--31
Article / Letter to editor
Display more detailsDisplay less details
Radiotherapy and Oncology
SubjectExperimental radiotherapy and neuro-oncology.; Experimentele radiotherapie en neuro-oncologie.
BACKGROUND AND PURPOSE: In interstitial hyperthermia, temperature measurements are mainly performed inside heating applicators, and therefore, give the maximum temperatures of a rather heterogeneous temperature distribution. The problem of how to estimate lesion temperatures using the multi-electrode current-source interstitial hyperthermia (MECS-IHT) system in the brain was studied. MATERIALS AND METHODS: Temperatures were measured within the electrodes and in an extra catheter at the edge of a 4 x 4 x 4.5 cm(3) glioblastoma multiforme resection cavity. From the temperature decays during a power-off period, information was obtained about local maximum and minimum tissue temperatures. The significance of these data was examined through model calculations. RESULTS: Maximum tissue temperatures could be estimated roughly by switching off all electrodes for about 5 s. Model calculations showed that the minimum tissue temperatures near a certain afterloading catheter correspond well with the temperature of the applicator inside, about 1 min after this applicator was switched off. CONCLUSIONS: Although the electrode temperatures read during heating are not suitable to assess the temperature distribution, it is feasible to heat the brain adequately using the MECS-IHT system with extra sensors outside the electrodes and/or application of decay methods.
Upload full text
Use your RU credentials (u/z-number and password) to log in with SURFconext to upload a file for processing by the repository team.