Cost-effectiveness of induction of labour at term with a Foley catheter compared to vaginal prostaglandin E(2) gel (PROBAAT trial)
SourceBjog : an International Journal of Obstetrics and Gynaecology, 120, 8, (2013), pp. 987-995
Article / Letter to editor
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Bjog : an International Journal of Obstetrics and Gynaecology
SubjectNCEBP 4: Quality of hospital and integrated care
OBJECTIVE: To assess the economic consequences of labour induction with Foley catheter compared to prostaglandin E2 gel. DESIGN: Economic evaluation alongside a randomised controlled trial. SETTING: Obstetric departments of one university and 11 teaching hospitals in the Netherlands. POPULATION: Women scheduled for labour induction with a singleton pregnancy in cephalic presentation at term, intact membranes and an unfavourable cervix; and without previous caesarean section. METHODS: Cost-effectiveness analysis from a hospital perspective. MAIN OUTCOME MEASURES: We estimated direct medical costs associated with healthcare utilisation from randomisation to 6 weeks postpartum. For caesarean section rate, and maternal and neonatal morbidity we calculated the incremental cost-effectiveness ratios, which represent the costs to prevent one of these adverse outcomes. RESULTS: Mean costs per woman in the Foley catheter group (n = 411) and in the prostaglandin E(2) gel group (n = 408), were euro3297 versus euro3075, respectively, with an average difference of euro222 (95% confidence interval -euro157 to euro633). In the Foley catheter group we observed higher costs due to longer labour ward occupation and less cost related to induction material and neonatal admissions. Foley catheter induction showed a comparable caesarean section rate compared with prostaglandin induction, therefore the incremental cost-effectiveness ratio was not informative. Foley induction resulted in fewer neonatal admissions (incremental cost-effectiveness ratio euro2708) and asphyxia/postpartum haemorrhage (incremental cost-effectiveness ratios euro5257) compared with prostaglandin induction. CONCLUSIONS: Foley catheter and prostaglandin E2 labour induction generate comparable costs.
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