Frequency-specific directed interactions in the human brain network for language
Publication year
2017Number of pages
6 p.
Source
Proceedings of the National Academy of Sciences USA, 114, 30, (2017), pp. 8083-8088ISSN
Publication type
Article / Letter to editor
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Organization
PI Group Neurobiology of Language
PI Group Statistical Imaging Neuroscience
Cognitive Neuroscience
SW OZ DCC PL
Journal title
Proceedings of the National Academy of Sciences USA
Volume
vol. 114
Issue
iss. 30
Languages used
English (eng)
Page start
p. 8083
Page end
p. 8088
Subject
110 000 Neurocognition of Language; 220 Statistical Imaging Neuroscience; DI-BCB_DCC_Theme 1: Language and Communication; Psycholinguistics; Radboudumc 7: Neurodevelopmental disorders DCMN: Donders Center for Medical NeuroscienceAbstract
The brain's remarkable capacity for language requires bidirectional interactions between functionally specialized brain regions. We used magnetoencephalography to investigate interregional interactions in the brain network for language while 102 participants were reading sentences. Using Granger causality analysis, we identified inferior frontal cortex and anterior temporal regions to receive widespread input and middle temporal regions to send widespread output. This fits well with the notion that these regions play a central role in language processing. Characterization of the functional topology of this network, using data-driven matrix factorization, which allowed for partitioning into a set of subnetworks, revealed directed connections at distinct frequencies of interaction. Connections originating from temporal regions peaked at alpha frequency, whereas connections originating from frontal and parietal regions peaked at beta frequency. These findings indicate that the information flow between language-relevant brain areas, which is required for linguistic processing, may depend on the contributions of distinct brain rhythms.
This item appears in the following Collection(s)
- Academic publications [204107]
- Donders Centre for Cognitive Neuroimaging [3410]
- Electronic publications [102382]
- Faculty of Medical Sciences [80531]
- Faculty of Social Sciences [27319]
- Open Access publications [71023]
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