Pharmacological Therapy of Tachyarrhythmias During Pregnancy
Publication year
2016Source
Arrhythmia & Electrophysiology Review, 5, 1, (2016), pp. 41-4ISSN
Publication type
Article / Letter to editor
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Organization
Cardiology
Journal title
Arrhythmia & Electrophysiology Review
Volume
vol. 5
Issue
iss. 1
Page start
p. 41
Page end
p. 4
Subject
Radboudumc 0: Other Research RIHS: Radboud Institute for Health SciencesAbstract
Tachyarrhythmias are the most frequently observed cardiac complications during pregnancy. The majority of these maternal and foetal arrhythmias are supraventricular tachyarrhythmias; ventricular tachyarrhythmias are rare. The use of anti-arrhythmic drugs (AADs) during pregnancy is challenging due to potential foetal teratogenic effects. Maintaining stable and effective therapeutic maternal drug levels is difficult due to haemodynamic and metabolic alterations. Pharmacological treatment of tachyarrhythmias is indicated in case of maternal haemodynamic instability or hydrops fetalis. Evidenc e regarding the efficacy and safety of AAD therapy during pregnancy is scarce and the choice of AAD should be based on individual risk assessments for both mother and foetus. This review outlines the current knowledge on the development of tachyarrhythmias during pregnancy, the indications for and considerations of pharmacological treatment and its potential side-effects.
This item appears in the following Collection(s)
- Academic publications [238441]
- Electronic publications [122544]
- Faculty of Medical Sciences [90373]
- Open Access publications [97535]
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