Liver Resection for Metastatic Disease; A Population-Based Analysis of Trends
Publication year
2016Source
Digestive Surgery, 33, 2, (2016), pp. 104-113ISSN
Publication type
Article / Letter to editor

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Organization
Surgery
Cognitive Neuroscience
Pathology
Journal title
Digestive Surgery
Volume
vol. 33
Issue
iss. 2
Page start
p. 104
Page end
p. 113
Subject
Radboudumc 14: Tumours of the digestive tract RIHS: Radboud Institute for Health Sciences; Radboudumc 14: Tumours of the digestive tract RIMLS: Radboud Institute for Molecular Life SciencesAbstract
OBJECTIVE: The study aims to evaluate all patients who underwent liver resection for metastatic disease for demographics, characteristics of the primary tumor and metastasis, volume of liver resection specimens per pathology laboratory and to describe trends in surgical treatment. METHODS: Data were prospectively collected using the Dutch nationwide pathology network. All pathology reports containing details on liver resections for metastatic disease between January 2001 and December 2010 were evaluated. RESULTS: A total of 3,916 liver resections were performed in 3,699 patients with a median age of 63 years (range 1-91). The primary tumor was mainly colorectal (n = 3,256; 88.0%). The number of 'high volume liver centers' increased from 2 to 12 in the study period, whereas the number of 'low volume centers' decreased. The number of liver resections increased from 224 to 596 per year (p </= 0.0001). A significant increase was demonstrated in elderly patients, patients with multiple metastases, liver resections for smaller metastases and minor liver resections. CONCLUSION: Although the majority of patients were young and had solitary metastasis, indications for liver resection are expanding as indicated by increasing numbers of elderly and patients with multiple liver metastases. Patients with non-colorectal liver metastases were seldom candidates for resection.
This item appears in the following Collection(s)
- Academic publications [189120]
- Electronic publications [87995]
- Faculty of Medical Sciences [74529]
- Open Access publications [57390]
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