Audioprofile Surfaces: The 21st Century Audiogram

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Title:	Audioprofile Surfaces: The 21st Century Audiogram
Author(s):	Taylor, K.R.; Booth, K.T.; Azaiez, H.; Sloan, C.M.; Kolbe, D.L.; Glanz, E.N.; Shearer, A.E.; DeLuca, A.P.; Anand, V.N.; Hildebrand, M.S.; Simpson, A.C.; Eppsteiner, R.W.; Scheetz, T.E.; Braun, T.A.; Huygen, P.L.M. ; Smith, R.J.; Casavant, T.L.
Publication year:	2016
Source:	Annals of Otology, Rhinology and Laryngology, vol. 125, iss. 5, (2016), pp. 361-368
ISSN:	0003-4894
Related links:	http://aor.sagepub.com/content/125/5/361.full.pdf
DOI:	https://doi.org/10.1177/0003489415614863
Publication type:	Article / Letter to editor
Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/168310
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Subject:	Radboudumc 12: Sensory disorders DCMN: Donders Center for Medical Neuroscience
Organization:	Otorhinolaryngology
Journal title:	Annals of Otology, Rhinology and Laryngology
Volume:	vol. 125
Issue:	iss. 5
Page start:	p. 361
Page end:	p. 368
Abstract:	OBJECTIVE: To present audiometric data in 3 dimensions by considering age as an addition dimension. METHODS: Audioprofile surfaces (APSs) were fitted to a set of audiograms by plotting each measurement of an audiogram as an independent point in 3 dimensions with the x, y, and z axes representing frequency, hearing loss in dB, and age, respectively. RESULTS: Using the Java-based APS viewer as a standalone application, APSs were pre-computed for 34 loci. By selecting APSs for the appropriate genetic locus, a clinician can compare this APS-generated average surface to a specific patient's audiogram. CONCLUSION: Audioprofile surfaces provide an easily interpreted visual representation of a person's hearing acuity relative to others with the same genetic cause of hearing loss. Audioprofile surfaces will support the generation and testing of sophisticated hypotheses to further refine our understanding of the biology of hearing.