Single acquisition electrical property mapping based on relative coil sensitivities: A proof-of-concept demonstration
Publication year
2015Source
Magnetic Resonance in Medicine, 74, (2015), pp. 185-195ISSN
Publication type
Article / Letter to editor

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Organization
PI Group MR Techniques in Brain Function
Journal title
Magnetic Resonance in Medicine
Volume
vol. 74
Page start
p. 185
Page end
p. 195
Subject
150 000 MR Techniques in Brain FunctionAbstract
PurposeAll methods presented to date to map both conductivity and permittivity rely on multiple acquisitions to compute quantitatively the magnitude of radiofrequency transmit fields, B-1(+). In this work, we propose a method to compute both conductivity and permittivity based solely on relative receive coil sensitivities (B-1(-)) that can be obtained in one single measurement without the need to neither explicitly perform transmit/receive phase separation nor make assumptions regarding those phases. Theory and MethodsTo demonstrate the validity and the noise sensitivity of our method we used electromagnetic finite differences simulations of a 16-channel transceiver array. To experimentally validate our methodology at 7 Tesla, multi compartment phantom data was acquired using a standard 32-channel receive coil system and two-dimensional (2D) and 3D gradient echo acquisition. The reconstructed electric properties were correlated to those measured using dielectric probes. ResultsThe method was demonstrated both in simulations and in phantom data with correlations to both the modeled and bench measurements being close to identity. The noise properties were modeled and understood. ConclusionThe proposed methodology allows to quantitatively determine the electrical properties of a sample using any MR contrast, with the only constraint being the need to have 4 or more receive coils and high SNR. Magn Reson Med 74:185-195, 2015. (c) 2014 Wiley Periodicals, Inc.
This item appears in the following Collection(s)
- Academic publications [234419]
- Donders Centre for Cognitive Neuroimaging [3724]
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