Publication year
2002Source
Canadian Journal of Neurological Sciences, 29, 4, (2002), pp. 375-377ISSN
Publication type
Article / Letter to editor

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Organization
Paediatrics - OUD tm 2017
Neurosurgery
Journal title
Canadian Journal of Neurological Sciences
Volume
vol. 29
Issue
iss. 4
Page start
p. 375
Page end
p. 377
Subject
Onderzoek NeurochirurgieAbstract
BACKGROUND: Symptomatic brain metastases from prostatic carcinoma are rare (0.05% to 0.5%). CASE REPORT: A 70-year-old man presented with a homonymous hemianopsia due to brain metastatic prostatic carcinoma shortly before becoming symptomatic of prostatic disease. CT and MRI of the brain showed a tumour deep in the right hemisphere near the thalamus and involving the optic radiation. RESULTS: Routine haematological and biochemical tests were normal. The prostate specific antigen level was low on two separate occasions. The prostatic and brain tumours showed identical appearances, namely of a poorly differentiated adenocarcinoma with neuroendocrine differentiation (small cell carcinoma). CONCLUSION: A literature review suggests that small cell carcinoma of the prostate is more likely to spread to the brain compared to adenocarcinoma and that brain metastases indicate a poor prognosis. The prostate gland should be remembered as a possible cause of brain metastases and that a normal serum prostate specific antigen does not exclude this diagnosis.
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- Academic publications [203793]
- Faculty of Medical Sciences [80320]
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