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Title: [Hemopyrrollactamuria (HPU); from spots to pseudo-disease]
Author(s): Meer, J.W.M. van der ; Kerkhof, R. van de; The, G.K.H. ; Boers, G.H.J.
Publication year: 2003
Source: Nederlands Tijdschrift voor Geneeskunde, vol. 147, iss. 36, (2003), pp. 1720-1721
ISSN: 0028-2162
Publication type: Article / Letter to editor

Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/165061   http://hdl.handle.net/2066/165061

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Subject: EBP 3: Effective Primary Care and Public Health
UMCN 4.1: Microbial pathogenesis and host defense
Organization: Internal Medicine
Journal title:
Nederlands Tijdschrift voor Geneeskunde
Volume: vol. 147
Issue: iss. 36
Page start: p. 1720
Page end: p. 1721
Abstract:
In recent years, patients in the Netherlands confront their doctors with the diagnosis 'haemopyrollactamuria' (HPU), based on the presence of the haemopyrrollactam complex in their urine. The diagnosis is made by a commercial laboratory in the Netherlands (www.keac.nl). We have not been able to find peer-reviewed scientific literature on this metabolic disease. The haemopyrrollactam complex represents the so-called mauve spot, which was the subject of much controversy in schizophrenia research in the previous century. Reviewing all of the available data, we feel that HPU should be classified as a pseudo-disease.

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