Pulmonary nodule detection in CT images: false positive reduction using multi-view convolutional networks
Publication year
2016Source
IEEE Transactions on Medical Imaging, 35, 5, (2016), pp. 1160-1169ISSN
Publication type
Article / Letter to editor

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Organization
Medical Imaging
Pathology
Journal title
IEEE Transactions on Medical Imaging
Volume
vol. 35
Issue
iss. 5
Page start
p. 1160
Page end
p. 1169
Subject
Radboudumc 14: Tumours of the digestive tract RIHS: Radboud Institute for Health Sciences; Radboudumc 9: Rare cancers RIHS: Radboud Institute for Health SciencesAbstract
We propose a novel Computer-Aided Detection (CAD) system for pulmonary nodules using multi-view convolutional networks (ConvNets), for which discriminative features are automatically learnt from the training data. The network is fed with nodule candidates obtained by combining three candidate detectors specifically designed for solid, subsolid, and large nodules. For each candidate, a set of 2-D patches from differently oriented planes is extracted. The proposed architecture comprises multiple streams of 2-D ConvNets, for which the outputs are combined using a dedicated fusion method to get the final classification. Data augmentation and dropout are applied to avoid overfitting. On 888 scans of the publicly available LIDCIDRI dataset, our method reaches high detection sensitivities of 85.4% and 90.1% at 1 and 4 false positives per scan, respectively. An additional evaluation on independent datasets from the ANODE09 challenge and DLCST is performed. We showed that the proposed multi-view ConvNets is highly suited to be used for false positive reduction of a CAD system.
This item appears in the following Collection(s)
- Academic publications [232036]
- Electronic publications [115285]
- Faculty of Medical Sciences [89029]
- Open Access publications [82630]
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