Women's and healthcare professionals' preferences for prenatal testing: a discrete choice experiment

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Title:	Women's and healthcare professionals' preferences for prenatal testing: a discrete choice experiment
Author(s):	Beulen, L.; Grutters, J.P.C.; Faas, B.H.W. ; Feenstra, I. ; Groenewoud, H. ; Vugt, J.M.G. van; Bekker, M.N.
Publication year:	2015
Source:	Prenatal Diagnosis, vol. 35, iss. 6, (2015), pp. 549-557
ISSN:	0197-3851
DOI:	https://doi.org/10.1002/pd.4571
Publication type:	Article / Letter to editor
Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/154468
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Subject:	Radboudumc 0: Other Research RIHS: Radboud Institute for Health Sciences Radboudumc 0: Other Research RIMLS: Radboud Institute for Molecular Life Sciences Radboudumc 10: Reconstructive and regenerative medicine RIMLS: Radboud Institute for Molecular Life Sciences Radboudumc 13: Stress-related disorders DCMN: Donders Center for Medical Neuroscience Radboudumc 15: Urological cancers RIHS: Radboud Institute for Health Sciences Radboudumc 9: Rare cancers RIHS: Radboud Institute for Health Sciences
Organization:	Gynaecology Health Evidence Operating Rooms Human Genetics
Journal title:	Prenatal Diagnosis
Volume:	vol. 35
Issue:	iss. 6
Page start:	p. 549
Page end:	p. 557
Abstract:	OBJECTIVE: This study evaluates pregnant women's and healthcare professionals' preferences regarding specific prenatal screening and diagnostic test characteristics. METHOD: A discrete choice experiment was developed to assess preferences for prenatal tests that differed in seven attributes: minimal gestational age, time to test results, level of information, detection rate, false positive rate, miscarriage risk and costs. RESULTS: The questionnaire was completed by 596 (70.2%) pregnant women and 297 (51.7%) healthcare professionals, of whom 507 (85.1%) and 283 (95.3%), respectively, were included in further analyses as their choice behavior indicated prenatal testing was an option to them. Comparison of results showed differences in relative importance attached to attributes, further reflected by differences in willingness to trade between attributes. Pregnant women are willing to accept a less accurate test to obtain more information on fetal chromosomal status or to exclude the risk of procedure-related miscarriage. Healthcare professionals consider level of information and miscarriage risk to be most important as well but put more emphasis on timing and accuracy. CONCLUSION: Pregnant women and healthcare professionals differ significantly in their preferences regarding prenatal test characteristics. Healthcare professionals should take these differences into consideration when counseling pregnant women on prenatal testing. (c) 2015 John Wiley & Sons, Ltd.