Anakinra Injection Site Reaction on FDG PET/CT

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Title:	Anakinra Injection Site Reaction on FDG PET/CT
Author(s):	Arens, A.I.J. ; Vriens, D. ; Janssen, M; Simon, A. ; Oyen, W.J.G.
Publication year:	2015
Source:	Clinical Nuclear Medicine, vol. 40, iss. 6, (2015), pp. 492-493
ISSN:	0363-9762
DOI:	https://doi.org/10.1097/RLU.0000000000000747
Publication type:	Article / Letter to editor
Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/154122
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Subject:	Radboudumc 5: Inflammatory diseases RIMLS: Radboud Institute for Molecular Life Sciences Radboudumc 9: Rare cancers RIMLS: Radboud Institute for Molecular Life Sciences
Organization:	Nuclear Medicine Radiology & Nuclear Medicine Internal Medicine
Journal title:	Clinical Nuclear Medicine
Volume:	vol. 40
Issue:	iss. 6
Page start:	p. 492
Page end:	p. 493
Abstract:	Adult-onset Still's disease (AOSD) is a rare inflammatory disorder of unknown etiology, mainly characterized by fever, arthritis, skin rash, and raised ferritin concentration. FDG PET/CT scan of a 29-year-old woman with AOSD showed extensive lymphadenopathy, hypermetabolic splenomegaly, and increased bone marrow uptake consistent with AOSD activity. In addition, large dense lesions with high FDG uptake in the subcutaneous fat in the thighs corresponding to injection sites were seen. She had been treated with prednisone and daily subcutaneous injection of 100 mg anakinra before the scan indicating the subcutaneous lesions as injection site reactions to anakinra.