Migratory polyarthritis as an adverse effect of thiamazole use in a 13-year-old girl with Graves' disease

There is no fulltext present in this item.

Title:	Migratory polyarthritis as an adverse effect of thiamazole use in a 13-year-old girl with Graves' disease
Author(s):	Janson, J.A.; Laat, P. de ; Draaisma, J.M.T.
Publication year:	2015
Source:	Journal of Pediatric Endocrinology & Metabolism, vol. 28, iss. 9-10, (2015), pp. 1169-1171
ISSN:	0334-018X
DOI:	https://doi.org/10.1515/jpem-2014-0433
Publication type:	Article / Letter to editor
Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/153393
Display more details
Subject:	Radboudumc 18: Healthcare improvement science RIHS: Radboud Institute for Health Sciences Radboudumc 6: Mitochondrial diseases RIMLS: Radboud Institute for Molecular Life Sciences
Organization:	Paediatrics
Journal title:	Journal of Pediatric Endocrinology & Metabolism
Volume:	vol. 28
Issue:	iss. 9-10
Page start:	p. 1169
Page end:	p. 1171
Abstract:	Graves' disease is the most prevalent cause of hyperthyroidism in children. The treatment commonly involves antithyroid therapy using a thionamide. We present a case of a 13-year-old girl with the antithyroid arthritis syndrome, presenting as a migratory polyarthritis, after the initiation of thionamide treatment for Graves' disease. Antithyroid arthritis syndrome warranted immediate cessation of thionamide. Improvement of the arthritis was seen in subsequent days. As there are no other reversible treatment modalities for Graves' disease in children, definitive treatment with radioactive iodine was needed to control the hyperthyroidism in this child. Antithyroid arthritis syndrome presenting as a migratory polyarthritis is a severe adverse effect of a common pediatric disease and should therefore be recognized by pediatricians.