Directed communication between nucleus accumbens and neocortex in humans is differentially supported by synchronization in the theta and alpha band
Publication year
2015Author(s)
Number of pages
20 p.
Source
PLoS One, 10, 9, (2015), article e0138685ISSN
Publication type
Article / Letter to editor

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Organization
PI Group Neuronal Oscillations
PI Group Neurobiology of Language
Psychiatry
PI Group Motivational & Cognitive Control
Neuroinformatics
Journal title
PLoS One
Volume
vol. 10
Issue
iss. 9
Languages used
English (eng)
Subject
110 000 Neurocognition of Language; 160 000 Neuronal Oscillations; 160 027 Frontal striatal interactions; 160 040 Catan; 170 000 Motivational & Cognitive Control; Neuroinformatics; Radboudumc 13: Stress-related disorders DCMN: Donders Center for Medical NeuroscienceAbstract
Here, we report evidence for oscillatory bi-directional interactions between the nucleus accumbens and the neocortex in humans. Six patients performed a demanding covert visual attention task while we simultaneously recorded brain activity from deep-brain electrodes implanted in the nucleus accumbens and the surface electroencephalogram (EEG). Both theta and alpha oscillations were strongly coherent with the frontal and parietal EEG during the task. Theta-band coherence increased during processing of the visual stimuli. Granger causality analysis revealed that the nucleus accumbens was communicating with the neocortex primarily in the theta-band, while the cortex was communicating the nucleus accumbens in the alpha-band. These data are consistent with a model, in which theta- and alpha-band oscillations serve dissociable roles: Prior to stimulus processing, the cortex might suppress ongoing processing in the nucleus accumbens by modulating alpha-band activity. Subsequently, upon stimulus presentation, theta oscillations might facilitate the active exchange of stimulus information from the nucleus accumbens to the cortex.
This item appears in the following Collection(s)
- Academic publications [202801]
- Donders Centre for Cognitive Neuroimaging [3354]
- Electronic publications [100942]
- Faculty of Medical Sciences [80020]
- Faculty of Science [31860]
- Open Access publications [69657]
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