E1AF expression levels are not associated with prognosis in human breast cancer.
SourceBreast Cancer Research and Treatment, 79, 1, (2003), pp. 129-131
Article / Letter to editor
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Breast Cancer Research and Treatment
SubjectUMCN 1.2: Molecular diagnosis, prognosis and monitoring; UMCN 5.2: Endocrinology and reproduction
E1AF is a transcription factor involved in regulation of several metastasis-associated genes, and is associated with overexpression of HER2/neu. We were unable to find a clear prognostic value of E1AF expression in human breast cancer. Furthermore, no association of E1AF levels with HER2/neu mRNA levels, hormone receptor status, histological grade, tumor size, or lymph node involvement was found.
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