Measuring the Neural Basis of Reward Anticipation and Reward Receipt in Attention-Deficit/Hyperactivity Disorder: The Importance of Task Design

Abstract

In the May 2015 issue of the Journal, von Rhein et al. investigated ventral-striatal (VS) response during monetary reward anticipation and receipt using an impressively large sample (N = 350) of adolescents and young adults with attention-deficit/hyperactivity disorder (ADHD), their unaffected siblings, and typically functioning controls. The goal was to resolve putative inconsistent findings in previous studies by using a statistically well-powered, multicenter, large-scale functional magnetic resonance imaging study.