Hyperhomocysteinemia as risk factor for ischemic and hemorrhagic stroke in newborn infants.
SourceJournal of Pediatrics, 141, 3, (2002), pp. 429-431
Article / Letter to editor
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Journal of Pediatrics
SubjectInborn errors of metabolism; Heartfunction and circulation; Erfelijke stofwisselingsziekten; Hartfunctie en circulatie
We studied the association between plasma total homocysteine concentrations and the occurrence of stroke in newborn infants (n = 24). Newborn infants with stroke had significantly higher mean total homocysteine concentrations compared with 94 healthy newborn infants (9.3 vs 7.4 micromol/L). The odds ratio for neonatal stroke was 3.95 (95" CI 1.53-10.16) at the 80" cutoff level.
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