Blood flow and muscle oxygen uptake at the onset and end of moderate and heavy dynamic forearm exercise.
Publication year
2001Source
American Journal of Physiology : Regulatory Integrative and Comparative Physiology, 280, 6, (2001), pp. R174-7ISSN
Publication type
Article / Letter to editor

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Organization
Neurology
Physiology
Journal title
American Journal of Physiology : Regulatory Integrative and Comparative Physiology
Volume
vol. 280
Issue
iss. 6
Page start
p. R174
Page end
p. 7
Subject
Bloodpressure regulation, tissue oxygenation and exercise; Neuromuscular and neurometabolic disorders; Bloeddrukregulatie, weefseloxygenatie en inspanning; Neuromusculaire en neurometabole aandoeningenAbstract
We hypothesized that forearm blood flow (FBF) during moderate intensity dynamic exercise would meet the demands of the exercise and that postexercise FBF would quickly recover. In contrast, during heavy exercise, FBF would be inadequate causing a marked postexercise hyperemia and sustained increase in muscle oxygen uptake (VO(2musc)). Six subjects did forearm exercise (1-s contraction/relaxation, 1-s pause) for 5 min at 25 and 75% of peak workload. FBF was determined by Doppler ultrasound, and O(2) extraction was estimated from venous blood samples. In moderate exercise, FBF and VO(2musc) increased within 2 min to steady state. Rapid recovery to baseline suggested adequate O(2) supply during moderate exercise. In contrast, FBF was not adequate during heavy dynamic exercise. Immediately postexercise, there was an approximately 50% increase in FBF. Furthermore, we observed for the first time in the recovery period an increase in VO(2musc) above end-exercise values. During moderate exercise, O(2) supply met requirements, but with heavy forearm exercise, inadequate O(2) supply during exercise caused accumulation of a large O(2) deficit that was repaid during recovery.
This item appears in the following Collection(s)
- Academic publications [204860]
- Faculty of Medical Sciences [81031]
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