Publication year
2014Source
American Journal of Medical Genetics. Part A, 164A, 11, (2014), pp. 2689-2700ISSN
Publication type
Article / Letter to editor

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Organization
Oral and Maxillofacial Surgery
Journal title
American Journal of Medical Genetics. Part A
Volume
vol. 164A
Issue
iss. 11
Page start
p. 2689
Page end
p. 2700
Subject
Radboudumc 18: Healthcare improvement science RIHS: Radboud Institute for Health SciencesAbstract
Simon van Creveld received both the MD and PhD degrees and had a multifaceted medical and scientific education at many hospitals and research institutes in the Netherlands, Germany, and the UK. He and his wife were the first to develop insulin for the Netherlands. His major interests were in hemophilia and hemorrhagic disorders, which accounted for 87 of his publications. In 1934, van Creveld demonstrated that a dispersed protein fraction obtained from serum could reduce the clotting time of hemophilic blood. His interest in glycogen storage disease resulted in van Creveld-von Gierke disease for which van Creveld contributed four published articles. The Ellis-van Creveld syndrome, also known as chondroectodermal dysplasia, was published in 1940 and became well known to medical geneticists. During the Nazi occupation of the Netherlands, van Creveld's professorship was taken away from him because he was Jewish. His visits to hospitals of concentration camps to treat babies and give pediatric advice while wearing a Jewish Yellow Star and interacting with SS Commandants in charge, and then leaving can only be described as amazing. After the war, his professorship was returned, and in the same year as his retirement, he established a large Hemophila Treatment and Research Center now known as the Van Creveld Clinic, which celebrated its 40th anniversary in 2005.
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- Faculty of Medical Sciences [81055]
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