TY - THES AU - Timmers, H.J.L.M. PY - 2004 SN - 9090180486 UR - https://hdl.handle.net/2066/59116 AB - Carotid baro- and chemoreceptors play an important role in blood pressure and blood gas homeostasis. Inadvertent denervation of these receptors in humans has been reported following surgery and radiotherapy in the area of the carotid bifurcation. The resulting syndrome of baroreflex failure is characterized by disabling labile hypertension. Chemoreflex failure results in abnormal ventilatory responsiveness to hypoxia. This thesis contains studies on the long-term effects of carotid body tumor surgery, carotid endarterectomy and jugular radiotherapy on baro- and chemoreflex function. The relative contribution of carotid receptors to baro- and chemoreflex function in humans is discussed PB - [S.l. : s.n.] TI - Denervation of carotid baro- and chemoreceptors in humans. N1 - KUN Katholieke Universiteit Nijmegen, 23 juni 2004 N1 - Promotor : Thien, Th. Co-promotores : Lenders, J.W.M., Karemaker, J.M., Wieling, W. L1 - https://repository.ubn.ru.nl/bitstream/handle/2066/59116/59116.pdf?sequence=1 ER -