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Publication year
2014Source
Pharmacology, Biochemistry and Behavior, 121, (2014), pp. 102-114ISSN
Annotation
1 juni 2014
Publication type
Article / Letter to editor

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Organization
Anatomy
Psychoneuropharmacology
Journal title
Pharmacology, Biochemistry and Behavior
Volume
vol. 121
Page start
p. 102
Page end
p. 114
Subject
Radboudumc 0: Other Research DCMN: Donders Center for Medical NeuroscienceAbstract
Serotonin plays an important role in male sexual behavior. Many studies have been performed on the pivotal role of 5-HT(1)A receptors in sexual behavior. Overall, 5-HT(1)A receptors do not appear to be involved under normal circumstances, but become very important under conditions of elevated serotonin levels in sexual behavior. 5-HT(1)A receptor agonists facilitate ejaculatory behavior in male rats, while inhibiting copulatory behavior. Three different phases can be distinguished in rats' sexual cycle, the introductory (precopulatory), the copulatory and the executive (ejaculatory) phases. Different mechanisms and brain regions are involved in these phases. The mechanisms, brain regions and the possible involvement of 5-HT and 5-HT(1)A receptors in the appropriate phases in male rat sexual behavior will be discussed in the current review.
This item appears in the following Collection(s)
- Academic publications [203812]
- Electronic publications [102110]
- Faculty of Medical Sciences [80326]
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