Publication year
2014Author(s)
Source
Seminars in Cell & Developmental Biology, 31C, (2014), pp. 132-140ISSN
Publication type
Article / Letter to editor

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Organization
Cell Biology (UMC)
Journal title
Seminars in Cell & Developmental Biology
Volume
vol. 31C
Page start
p. 132
Page end
p. 140
Subject
Radboudumc 17: Women's cancers RIMLS: Radboud Institute for Molecular Life SciencesAbstract
Building the complex architecture of tubular organs is a highly dynamic process that involves cell migration, polarization, shape changes, adhesion to neighboring cells and the extracellular matrix, physicochemical characteristics of the extracellular matrix and reciprocal signaling with the mesenchyme. Understanding these processes in vivo has been challenging as they take place over extended time periods deep within the developing organism. Here, I will discuss 3D in vitro models that have been crucial to understand many of the molecular and cellular mechanisms and key concepts underlying branching morphogenesis in vivo.
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- Academic publications [203856]
- Faculty of Medical Sciences [80326]
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