Fulltext present in this item

Thumbnail
Fulltext: 128550.pdf
Format: PDF
Description: publisher's version
Title: Physical activity is related to the structural integrity of cerebral white matter
Author(s): Gons, R.A.R. ; Tuladhar, A.M. ; Laat, K.F. de ; Norden, A.G.W. van ; Dijk, E.J. van ; Norris, D.G. ; Zwiers, M.P. ; Leeuw, F.E. de
Publication year: 2013
Source: Neurology, vol. 81, iss. 11, (2013), pp. 971-976
ISSN: 0028-3878
DOI: https://doi.org/10.1212/WNL.0b013e3182a43e33
Publication type: Article / Letter to editor

Please use this identifier to cite or link to this item : https://hdl.handle.net/2066/128550   https://hdl.handle.net/2066/128550

Display more details
Subject: 150 000 MR Techniques in Brain Function
Biophysics
DCN MP - Plasticity and memory
DCN MP - Plasticity and memory NCEBP 14: Cardiovascular diseases
DCN NN - Brain networks and neuronal communication
DCN NN - Brain networks and neuronal communication NCEBP 9 - Mental health
DCN PAC - Perception action and control
Organization: Neurology
Donders Centre for Cognitive Neuroimaging
PI Group MR Techniques in Brain Function
Cognitive Neuroscience
Journal title:
Neurology
Volume: vol. 81
Issue: iss. 11
Page start: p. 971
Page end: p. 976
Abstract:
OBJECTIVE: To investigate the relation between physical exercise and the microstructural integrity of cerebral white matter. METHODS: Four hundred forty individuals with cerebral small-vessel disease, aged between 50 and 85 years, without dementia, were included and underwent MRI scanning. Physical exercise was assessed with a structured questionnaire. The cross-sectional relation between physical exercise and the microstructural integrity of the white matter was assessed by applying Tract-Based Spatial Statistics to diffusion tensor imaging parameters. RESULTS: Being more physically active was negatively related to the mean, axial, and radial diffusivity in numerous regions of the white matter, indicative of higher white matter integrity. CONCLUSIONS: These data indicate an association between physical activity and the integrity of the cerebral white matter's microstructure. Prospective studies are required to investigate a possible causal association between physical activity and cognitive decline.

This item appears in the following Collection(s)

Browse

Statistics