An electroconvulsive therapy procedure impairs reconsolidation of episodic memories in humans
until further notice
Number of pages
SourceNature Neuroscience, 17, 2, (2014), pp. 204-206
Article / Letter to editor
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PI Group Memory & Emotion
Subject130 000 Cognitive Neurology & Memory; Radboudumc 13: Stress-related disorders DCMN: Donders Center for Medical Neuroscience
Despite accumulating evidence for a reconsolidation process in animals, support in humans, especially for episodic memory, is limited. Using a within-subjects manipulation, we found that a single application of electroconvulsive therapy following memory reactivation in patients with unipolar depression disrupted reactivated, but not non-reactivated, memories for an emotional episode in a time-dependent manner. Our results provide evidence for reconsolidation of emotional episodic memories in humans.
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