Repetitive transcranial magnetic stimulation over the right dorsolateral prefrontal cortex affects strategic decision-making
SourceNeuroreport, 16, 16, (2005), pp. 1849-1852
Article / Letter to editor
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SW OZ BSI SCP
PI Group Decision Neuroscience
Donders Centre for Cognitive Neuroimaging
SubjectBehaviour Change and Well-being
Although decision-making is typically seen as a rational process, emotions play a role in tasks that include unfairness. Recently, activation in the right dorsolateral prefrontal cortex during offers experienced as unfair in the Ultimatum Game was suggested to subserve goal maintenance in this task. This is restricted to correlational evidence, however, and it remains unclear whether the dorsolateral prefrontal cortex is crucial for strategic decision-making. The present study used repetitive transcranial magnetic stimulation in order to investigate the causal role of the dorsolateral prefrontal cortex in strategic decision-making in the Ultimatum Game. The results showed that repetitive transcranial magnetic stimulation over the right dorsolateral prefrontal cortex resulted in an altered decision-making strategy compared with sham stimulation. We conclude that the dorsolateral prefrontal cortex is causally implicated in strategic decision-making in healthy human study participants.
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