Unraveling the mechanisms underlying postural instability in Parkinson's disease using dynamic posturography
Publication year
2013Source
Expert Review of Neurotherapeutics, 13, 12, (2013), pp. 1303-8ISSN
Publication type
Article / Letter to editor
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Organization
Rehabilitation
Neurology
Journal title
Expert Review of Neurotherapeutics
Volume
vol. 13
Issue
iss. 12
Page start
p. 1303
Page end
p. 8
Subject
DCN MP - Plasticity and memory NCEBP 10: Human Movement & Fatigue; NCEBP 10: Human Movement & Fatigue DCN PAC - Perception action and controlAbstract
Postural instability, one of the cardinal symptoms of Parkinson's disease (PD), has devastating consequences for affected patients. Better strategies to prevent falls are needed, but this calls for an improved understanding of the complex mechanisms underlying postural instability. We must also improve our ability to timely identify patients at risk of falling. Dynamic posturography is a promising avenue to achieve these goals. The latest moveable platforms can deliver 'real-life' balance perturbations, permitting study of everyday fall circumstances. Dynamic posturography studies have shown that PD patients have fundamental problems in scaling their postural responses in accordance with the need of the actual balance task at hand. On-going studies evaluate the predictive ability of impaired posturography performance for daily life falls. We also review recent work aimed at exploring balance correcting steps in PD, and the presumed interaction between startle pathways and postural responses.
This item appears in the following Collection(s)
- Academic publications [238430]
- Faculty of Medical Sciences [90359]
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