Norovirus genogroup II gastroenteritis in hospitalized children in South India
SourceAmerican Journal of Tropical Medicine and Hygiene, 89, 5, (2013), pp. 1019-1022
Article / Letter to editor
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American Journal of Tropical Medicine and Hygiene
SubjectN4i 1: Pathogenesis and modulation of inflammation
The distribution of norovirus (NoV) genogroup II in children < 5 years of age admitted to a south Indian hospital with diarrhea was investigated. Viral RNA extracted from 282 stool samples were screened for NoV GII and positive amplicons sequenced. Twenty-eight (9.9%) had NoV GII infection with a median age of 6 months, with more severe episodes of diarrhea among infected (median Vesikari score 13, interquartile range [IQR] 10-15) than children without infection (median score 10, IQR 8-13, P = 0.002). The study documents NoV GII infections as an important cause of gastroenteritis and the genetic diversity of circulating strains.
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