Co-segregation of Social Cognition, Executive Function and Local Processing Style in Children with ASD, their Siblings and Normal Controls
Publication year
2013Source
Journal of Autism and Developmental Disorders, 43, 12, (2013), pp. 2764-78ISSN
Publication type
Article / Letter to editor
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Organization
Cognitive Neuroscience
Psychiatry
PI Group Memory & Emotion
Former Organization
Donders Centre for Cognitive Neuroimaging
Journal title
Journal of Autism and Developmental Disorders
Volume
vol. 43
Issue
iss. 12
Page start
p. 2764
Page end
p. 78
Subject
DCN PAC - Perception action and control NCEBP 9 - Mental health; NCEBP 9: Mental HealthAbstract
Cognitive research proposes that social cognition (SC), executive functions (EF) and local processing style (weak CC) may be fruitful areas for research into the familial-genetic underpinnings of Autism Spectrum Disorders (ASD). The performance of 140 children with ASD, 172 siblings and 127 controls on tasks measuring SC (face recognition, affective prosody, and facial emotion recognition), EF (inhibition, cognitive flexibility, and verbal working memory) and local processing style was assessed. Compelling evidence was found for the interrelatedness of SC and EF, but not local processing style, within individuals and within families, suggesting that these domains tend to co-segregate in ASD. Using the underlying shared variance of these constructs in genetic research may increase the power for detecting susceptibility genes for ASD.
This item appears in the following Collection(s)
- Academic publications [246164]
- Donders Centre for Cognitive Neuroimaging [4036]
- Faculty of Medical Sciences [93268]
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