Publication year
2003Source
Antimicrobial Agents and Chemotherapy, 47, 11, (2003), pp. 3647-3650ISSN
Publication type
Article / Letter to editor

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Organization
Medical Microbiology
Journal title
Antimicrobial Agents and Chemotherapy
Volume
vol. 47
Issue
iss. 11
Page start
p. 3647
Page end
p. 3650
Subject
UMCN 4.1: Microbial pathogenesis and host defenseAbstract
Three isolates of zygomycetes were used to produce a disseminated infection in nonimmunocompromised mice. Against all zygomycete strains, amphotericin B significantly prolonged survival. Itraconazole was inactive against Rhizopus microsporus and Rhizopus oryzae but was partially active against Absidia corymbifera. Posaconazole had no beneficial effects against R. oryzae but showed partial activity against A. corymbifera. Posaconazole had a clear dose-response effect against R. microsporus.
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- Academic publications [202863]
- Faculty of Medical Sciences [80039]
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