TY  - JOUR
AU  - Jensen, O.
AU  - Mazaheri, A.
PY  - 2010
UR  - https://hdl.handle.net/2066/89275
AB  - In order to understand the working brain as a network, it is essential to identify the mechanisms by which information is gated between regions. We here propose that information is gated by inhibiting task-irrelevant regions, thus routing information to task-relevant regions. The functional inhibition is reflected in oscillatory activity in the alpha band (8-13 Hz). From a physiological perspective the alpha activity provides pulsed inhibition reducing the processing capabilities of a given area. Active processing in the engaged areas is reflected by neuronal synchronization in the gamma band (30-100 Hz) accompanied by an alpha band decrease. According to this framework the brain could be studied as a network by investigating cross-frequency interactions between gamma and alpha activity. Specifically the framework predicts that optimal task performance will correlate with alpha activity in task-irrelevant areas. In this review we will discuss the empirical support for this framework. Given that alpha activity is by far the strongest signal recorded by EEG and MEG, we propose that a major part of the electrophysiological activity detected from the working brain reflects gating by inhibition.
TI  - Shaping functional architecture by oscillatory alpha activity: gating by inhibition.
SN  - 1662-5161
JF  - Frontiers in Human Neuroscience
VL  - vol. 4
DO  - https://doi.org/10.3389/fnhum.2010.00186
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/89275/89275.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Mazaheri, A.
AU  - Jensen, O.
PY  - 2010
UR  - https://hdl.handle.net/2066/89381
AB  - The conventional assumption in human cognitive electrophysiology using EEG and MEG is that the presentation of a particular event such as visual or auditory stimuli evokes a "turning on" of additional brain activity that adds to the ongoing background activity. Averaging multiple event-locked trials is thought to result in the cancellation of the seemingly random phased ongoing activity while leaving the evoked response. However, recent work strongly challenges this conventional view and demonstrates that the ongoing activity is not averaged out due to specific non-sinusoidal properties. As a consquence, systematic modulations in ongoing activity can produce slow cortical evoked responses reflecting cognitive processing. In this review we introduce the concept of "rhythmic pulsing" to account for this specific non-sinusoidal property. We will explain how rhythmic pulsing can create slow evoked responses from a physiological perspective. We will also discuss how the notion of rhythmic pulsing provides a unifying framework linking ongoing oscillations, evoked responses and the brain's capacity to process incoming information.
TI  - Rhythmic pulsing: linking ongoing brain activity with evoked responses.
SN  - 1662-5161
JF  - Frontiers in Human Neuroscience
VL  - vol. 4
DO  - https://doi.org/10.3389/fnhum.2010.00177
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/89381/89381.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Mazaheri, A.
AU  - Jensen, O.
PY  - 2010
UR  - https://hdl.handle.net/2066/115477
TI  - Rhythmic Pulsing: Linking ongoing brain activity with evoked responses
EP  - 13
SN  - 1662-5161
SP  - 1
JF  - Frontiers in Human Neuroscience
VL  - vol. 4
DO  - https://doi.org/10.3389/fnhum.2010.00177
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/115477/115477.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Jensen, O.
AU  - Mazaheri, A.
PY  - 2010
UR  - https://hdl.handle.net/2066/115479
TI  - Shaping functional architecture by oscillatory alpha activity: gating by inhibition
EP  - 8
SN  - 1662-5161
SP  - 1
JF  - Frontiers in Human Neuroscience
VL  - vol. 4
DO  - https://doi.org/10.3389/fnhum.2010.00186
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/115479/115479.pdf?sequence=1
ER  -