Tractography demonstrates dentate-rubro-thalamic tract disruption in an adult with cerebellar mutism

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Title:	Tractography demonstrates dentate-rubro-thalamic tract disruption in an adult with cerebellar mutism
Author(s):	Baarsen, K. van; Kleinnijenhuis, D.H. ; Konert, T.; Walsum, A.M. van Cappellen v; Grotenhuis, A.
Publication year:	2013
Source:	Cerebellum, vol. 12, iss. 5, (2013), pp. 617-622
ISSN:	1473-4222
DOI:	http://dx.doi.org/10.1007/s12311-013-0473-z
Publication type:	Article / Letter to editor
Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/119215
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Subject:	DCN NN - Brain networks and neuronal communication NCEBP 2: Evaluation of complex medical interventions ONCOL 5: Aetiology, screening and detection
Organization:	Neurosurgery Anatomy
Journal title:	Cerebellum
Volume:	vol. 12
Issue:	iss. 5
Page start:	p. 617
Page end:	p. 622
Abstract:	A 55-year-old female is presented with transient cerebellar mutism caused by a well-circumscribed left pontine infarction due to postoperative basilar perforator occlusion. Although conventional T2 imaging shows a well-demarcated lesion confined to the pontine region, diffusion tensor imaging shows an asymmetry in fractional anisotropy in the superior cerebellar peduncle. This supports the general hypothesis that cerebellar mutism is caused by functional disruption of the dentate-rubro-thalamic tract. Correlating postoperative anatomic changes to a heterogenic clinical syndrome remains challenging, however.