Tractography demonstrates dentate-rubro-thalamic tract disruption in an adult with cerebellar mutism
Publication year
2013Source
Cerebellum, 12, 5, (2013), pp. 617-22ISSN
Publication type
Article / Letter to editor

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Organization
Neurosurgery
Anatomy
Journal title
Cerebellum
Volume
vol. 12
Issue
iss. 5
Page start
p. 617
Page end
p. 22
Subject
DCN NN - Brain networks and neuronal communication; NCEBP 2: Evaluation of complex medical interventions ONCOL 5: Aetiology, screening and detectionAbstract
A 55-year-old female is presented with transient cerebellar mutism caused by a well-circumscribed left pontine infarction due to postoperative basilar perforator occlusion. Although conventional T2 imaging shows a well-demarcated lesion confined to the pontine region, diffusion tensor imaging shows an asymmetry in fractional anisotropy in the superior cerebellar peduncle. This supports the general hypothesis that cerebellar mutism is caused by functional disruption of the dentate-rubro-thalamic tract. Correlating postoperative anatomic changes to a heterogenic clinical syndrome remains challenging, however.
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- Academic publications [204968]
- Faculty of Medical Sciences [81049]
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